Thermo Fisher Scientific EDR1/PHC1 Polyclonal Antibody
EDR1/PHC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific EDR1/PHC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human EDR1/PHC1, amino acids 751–900 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Polycomb group (PcG) proteins assemble into multimeric protein complexes that maintain transcriptional repression of genes throughout development.
PHC1 (polyhomeotic homolog 1), also known as EDR1, HPH1, or RAE28, is a 1,004 amino acid nuclear protein and a component of the PcG multiprotein PRC1 complex.
The PRC1 complex modifies histones, remodels chromatin, and mediates monoubiquitination of Histone H2A.
PHC1 exists as a homodimer and contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain.
It is encoded by a gene located on human chromosome 12, which comprises approximately 4.5% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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