Thermo Fisher Scientific NGAL Monoclonal Antibody (04)

Thermo Fisher Scientific NGAL Monoclonal Antibody (Clone 04)

Applications

• Western Blot (WB): Assay-dependent
• ELISA: Assay-dependent

Product Specifications

Product Specific Information

• Specificity: ABS 038-04-02 does not cross-react with NGAL from other mammalian species tested.
• Reactivity: Binds human NGAL in solution and coated onto a solid phase.
• Application Note: Can be used as a capture antibody in sandwich ELISA with biotinylated detection antibodies HYB 211-01-02, ABS 038-14-02, ABS 038-15-02, and ABS 038-23-02.
• Concentration Notice: Lot-dependent, varies between 0.85–1.15 mg/mL.

Target Information

NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin, and neutrophil lipocalin) is a 25 kDa glycosylated single-chain monomer and member of the lipocalin family that binds and transports small lipophilic molecules. It is released by activated neutrophils, can form dimers or higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). NGAL expression is upregulated in inflammation and cancers and markedly increased in kidneys following ischemic or nephrotoxic injury.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.