Thermo Fisher Scientific EIF4G3 Monoclonal Antibody (1H5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

ELISA (ELISA)

1 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

1H5

Immunogen

EIF4G3 (AAH30578, 1 a.a. approximately 515 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:eIF4G3,uniProtId:O43432-1,ncbiNodeId:9606,antigenRange:1-1585,antigenLength:1585,antigenImageFileName:H00008672-M03_eIF4G3_O43432-1_House_mouse.svg,antigenImageFileNamePDP:H00008672-M03_eIF4G3_O43432-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MNSQPQTRSP FAAGPRPPHH QFFQRPQIQP PRATIPNSSP SIRPGAQTPT AVYQANQHIM MVNHLPMPYP VPQGPQYCIP QYRHSGPPYV GPPQQYPVQP PGPGPFYPGP GPGDFPNAYG TPFYPSQPVY QSAPIMVPTQ QQPPPAKREK KTIRIRDPNQ GGKDITEEII SGGGSRNPTP PIGRPTSTPT PPQQLPSQVP EHSPVVYGTV ESAHLAASTP VTAASDQKQE EKPKPDPVLK SPSPVLRLVL SGEKKEQEGQ TSETTAIVSI AELPLPPSPT TVSSVARSTI AAPTSSALSS QPIFTTAIDD RCELSSPRED TIPIPSLTSC TETSDPLPTN ENDGDICKKP CSVAPNDIPL VSSTNLINEI NGVSEKLSAT ESIVEIVKQE VLPLTLELEI LENPPEEMKL ECIPAPITPS TVPSFPPTPP TPPASPPHTP VIVPAAATTV SSPSAAITVQ RVLEEDESIR TCLSEDAKEI QNKIEVEADG QTEEILDSQN LNSRRSPVPE TSNEC

Target Information

The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.