Thermo Fisher Scientific CRHR1 Polyclonal Antibody
CRHR1 단백질을 인식하는 Thermo Fisher Scientific의 염소 다클론 항체로, 인간 및 마우스에 반응합니다. WB, IHC(P), ICC/IF에 사용 가능하며, 스트레스 반응 및 쿠싱병 관련 연구에 적합합니다. 액상 형태로 -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KLYYDNEKCWFGKR) corresponding to the internal amino acids of CRHR1 (aa 279–292). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983269 |
Product Specific Information
This antibody is predicted to react with bovine, canine, human, ovine, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 1,000.
Target Information
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1) is involved in mediating the stress response and anxiety-related behaviors. Mutations in this receptor may reduce anxiety-related behaviors and contribute to the pathogenesis of Cushing disease.
Multiple isoforms of CRFR1 are produced by alternative splicing. CRFR1 expression has been reported in pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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