Thermo Fisher Scientific NSUN6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NSUN6. Recombinant protein control fragment (Product #RP-97123). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NSUN6,uniProtId:Q8TEA1-1,ncbiNodeId:9606,antigenRange:95-187,antigenLength:469,antigenImageFileName:PA5-61119_NSUN6_Q8TEA1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61119_NSUN6_Q8TEA1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644825

Product Specific Information

Immunogen sequence: VLLIPVIGPR KNIKKQQCEA IVGAQCGNAV LRGAHVYAPG IVSASQFMKA GDVISVYSDI KGKCKKGAKE FDGTKVFLGN GISELSRKEI FSG

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.

Target Information

NSun6 is an RNA methyltransferase that catalyzes the methylation at position cytosine C72 in some tRNAs. NSUN6 has been reported to localize to the cytoplasm and largely colocalize with Golgi apparatus and pericentriolar matrix, indicating that NSUN6 modifies tRNAs in a late step in their biogenesis. NSun6 may also play a major role in bone metastasis and could be a valuable therapeutic target for bone metastasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.