Thermo Fisher Scientific TCF12 Monoclonal Antibody (OTI2E11), TrueMAB
TCF12 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, PBS/BSA/glycerol 완충액에 보존됩니다. 연구용 전용 시약으로 T세포 분화 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E11 |
| Immunogen | Full length human recombinant protein of human TCF12 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TCF12 (Transcription Factor 12), also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG.
It is expressed in various tissues such as skeletal muscle, thymus, B- and T-cells, and may regulate lineage-specific gene expression through heterodimer formation with other bHLH E-proteins.
TCF12, together with E2A, is essential for blocking thymocyte proliferation before pre-TCR expression and is critical for proper T cell differentiation.
Recent studies indicate that TCF12 also plays a key role in the development of invariant natural killer T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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