ELK Biotechnology OPG rabbit pAb
OPG rabbit pAb는 인간 및 생쥐 시료에 반응하는 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 TR11B 유래 펩타이드로부터 제작되었으며, 뼈 흡수 조절 및 림프절 형성 연구에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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제품명
OPG rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | TNFRSF11B; OCIF; OPG; Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 IHC-p: 1/100–1/300 ELISA: 1/20000 IF: 1/100–1/300 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TR11B (AA range: 10–59) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kD |
| Gene ID (Human) | 4982 |
| Human Swiss-Prot No. | O00300 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Mouse |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. It specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart suggest roles in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants have been reported, though their full-length nature has not been determined.
(Provided by RefSeq, Jul 2008)
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