ELK Biotechnology MYSM1 rabbit pAb
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카탈로그 번호 | 설명 | 상태 | 단위 | 가격 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
ES2883-100UL | ELK Biotechnology ES2883-100UL MYSM1 rabbit pAb, 100UL pk | 재고문의 | pk | 469,000원 | 515,900원 | |
ES2883-50UL | ELK Biotechnology ES2883-50UL MYSM1 rabbit pAb, 50UL pk | 재고문의 | pk | 320,000원 | 352,000원 |
다른 상품 둘러보기
Product name: | MYSM1 rabbit pAb |
Alternative Names: | MYSM1; KIAA1915; Histone H2A deubiquitinase MYSM1; 2A-DUB; Myb-like; SWIRM and MPN domain-containing protein 1 |
Applications: | WB;IHC;IF;ELISA |
Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human MYSM1. AA range:520-569 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 95kD |
GeneID(Human): | 114803 |
Human Swiss-Prot No: | Q5VVJ2 |
Cellular localization: | Nucleus . Cytoplasm . Localizes to the cytoplasm in response to bacterial infection. . |
Background: | catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,domain:Binds double-stranded DNA via the SANT domain. The SWIRM domain does not bind double-stranded DNA.,function:Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase M67A family. MYSM1 subfamily.,similarity:Contains 1 MPN (JAB/Mov34) domain.,similarity:Contains 1 SANT domain.,similarity:Contains 1 SWIRM domain.,subunit:Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones., |
Species Reactivity: | Human;Rat;Mouse; |
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