ELK Biotechnology Myomesin-2 rabbit pAb
Myomesin-2 단백질을 인식하는 토끼 폴리클로날 항체로, WB, ELISA, IHC에 사용 가능. 사람, 마우스, 원숭이에 반응하며 세포질 및 근절 M선에 위치. 고순도 IgG, 1 mg/ml 농도로 제공. -20°C에서 1년 보관 가능.
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Myomesin-2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Myomesin-2 rabbit pAb |
| Alternative Names | MYOM2; Myomesin-2; 165 kDa connectin-associated protein; 165 kDa titin-associated protein; M-protein; Myomesin family member 2 |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–1:20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MYOM2. AA range: 612–661 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 165 kD |
| GeneID (Human) | 9172 |
| Human Swiss-Prot No | P54296 |
| Cellular localization | Cytoplasm, myofibril, sarcomere, M line |
| Species Reactivity | Human; Mouse; Monkey |
Background
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
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