ELK Biotechnology MOR-1 rabbit pAb

제품 설명

ELK Biotechnology MOR-1 rabbit pAb는 인간, 마우스, 랫트에서 MOR-1(Mu-type opioid receptor)을 검출하기 위한 토끼 다클론 항체입니다.
이 항체는 다양한 응용 분야(WB, IHC, IF, ELISA)에 사용할 수 있으며, 합성 펩타이드 면역원으로부터 제작되었습니다.

제품 정보

Background

This gene encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. It also plays a role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via modulation of the dopamine system.
The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity, though evidence for a causal role is conflicting. Multiple transcript variants encoding different isoforms have been identified. The canonical MOR belongs to the 7-transmembrane-spanning G-protein-coupled receptor superfamily, though some isoforms have only 6 transmembrane domains.