ELK Biotechnology MEK-4 rabbit pAb
Human SEK1/MKK4 유래 펩타이드로 제작된 rabbit polyclonal antibody로 MAPK 신호전달 연구에 적합. WB, ELISA, IHC에 사용 가능하며 세포 내 MAPK 활성 조절 및 분화 연구에 활용. -20°C에서 1년 보관 가능.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology MEK-4 rabbit pAb
ELK Biotechnology MEK-4 rabbit pAb
제품 개요
MEK-4 rabbit pAb는 인간 SEK1/MKK4에서 유래한 합성 펩타이드로부터 생성된 rabbit polyclonal antibody입니다. MAPK 신호전달 경로에 관여하는 단백질 검출에 적합하며, 다양한 생물학적 과정(세포 증식, 분화, 전사 조절 등)의 연구에 활용됩니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Product name | MEK-4 rabbit pAb |
| Alternative Names | MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; MAPKK 4; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated pro |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized peptide derived from human SEK1/MKK4 (AA range: 46–95) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 44 kDa |
| GeneID (Human) | 6416 |
| Human Swiss-Prot No | P45985 |
| Cellular Localization | Cytoplasm, Nucleus |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as integration points for multiple biochemical signals and are involved in various cellular processes such as proliferation, differentiation, transcription regulation, and development.
MAPK proteins form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues.
In mouse, a similar protein has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
[provided by RefSeq, Jul 2013]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.