ELK Biotechnology KIR2.1 rabbit pAb
KIR2.1 rabbit pAb는 인간 KCNJ2 유래 펩타이드로부터 제작된 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 적합하며 세포막 단백질 검출에 유용합니다. 고순도 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
KIR2.1 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | KCNJ2; IRK1; Inward rectifier potassium channel 2; Cardiac inward rectifier potassium channel; Inward rectifier K(+) channel Kir2.1; IRK-1; hIRK1; Potassium channel; inwardly rectifying subfamily J member 2 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human KCNJ2 (AA range: 81–130) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 48 kD |
| GeneID (Human) | 3759 |
| Human Swiss-Prot No | P63252 |
| Cellular Localization | Membrane; Multi-pass membrane protein; Lipid-anchor |
| Species Reactivity | Human; Rat |
배경 정보
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses.
The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel.
It has a greater tendency to allow potassium to flow into a cell rather than out of a cell, and likely contributes to establishing action potential waveform and excitability of neuronal and muscle tissues.
Mutations in this gene have been associated with Andersen syndrome, characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.
(Provided by RefSeq, Jul 2008)
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