
ELK Biotechnology JIK rabbit pAb
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Product name: | JIK rabbit pAb |
Alternative Names: | TAOK3; DPK; JIK; KDS; MAP3K18; Serine/threonine-protein kinase TAO3; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase; Jun kinase-inhi |
Applications: | WB;ELISA;IHC |
Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
Immunogen: | The antiserum was produced against synthesized peptide derived from human TAOK3. AA range:531-580 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 110kD |
GeneID(Human): | 51347 |
Human Swiss-Prot No: | Q9H2K8 |
Cellular localization: | Cytoplasm . Cell membrane ; Peripheral membrane protein . Also localized to the peripheral cell membrane. |
Background: | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver., |
Species Reactivity: | Human;Mouse;Rat |
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