Thermo Fisher Scientific MAPK1 Polyclonal Antibody, Biotin
MAPK1(ERK2) 단백질을 인식하는 Biotin 결합 폴리클로날 항체로, Western Blot, IHC, ELISA, IP 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, 고순도 Affinity chromatography로 정제된 액상 제품입니다.
- 카탈로그번호
- MAPK1-Y-BIOTIN
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 300–350 on human Mitogen-activated protein kinase 1 (MAPK1/ERK2, UniProt ID: P28482-1) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), serve as integration points for multiple biochemical signals and participate in various cellular processes such as proliferation, differentiation, transcription regulation, and development. Activation requires phosphorylation by upstream kinases, after which MAPK1 translocates to the nucleus to phosphorylate nuclear targets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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