Thermo Fisher Scientific P2Y12 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human P2Y12. Validated for IHC-P and ICC/IF. Suitable for detecting P2Y12 expression in platelets and neural tissues. Supplied in liquid form at 1 mg/mL, purified by antigen affinity chromatography. For research u...
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 32 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH, corresponding to the N-terminal extracellular domain of human P2Y12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2155970 |
Product Specific Information
PA1-20758 detects P2Y12 in human samples.
Target Information
P2Y12 belongs to the family of G-protein coupled receptors. This family includes several receptor subtypes with overlapping pharmacological selectivity for various adenosine and uridine nucleotides. P2Y12 is involved in platelet aggregation and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified. Expression of P2Y12 has been reported in platelets, spinal cord, and multiple brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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