Thermo Fisher Scientific TPM4 Polyclonal Antibody
TPM4 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체로, WB 및 IHC(P) 실험에 적합. 인간, 마우스, 돼지 반응성. 액상 형태로 제공되며 안정적인 TBS 버퍼에 보존. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Pig |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-ENVGLHQTLDQ (aa 230–240) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933801 |
Product Specific Information
- Expected to recognize both reported isoforms (NP_001138632.1; NP_003281.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium-dependent regulation of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments, providing stability and regulating access of other actin-binding proteins. In muscle cells, they regulate contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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