Thermo Fisher Scientific TPM4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1-0.3 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

2.5 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Pig

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence C-ENVGLHQTLDQ (aa 230-240). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TPM4,uniProtId:P67936-1,ncbiNodeId:9606,antigenRange:230-240,antigenLength:248,antigenImageFileName:PA5-143162_TPM4_P67936-1_Goat.svg,antigenImageFileNamePDP:PA5-143162_TPM4_P67936-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2933801

Product Specific Information

Additional Information: This antibody is expected to recognize both reported isoforms (NP_001138632.1; NP_003281.1).

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Target Information

TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium dependent regulations of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.