Thermo Fisher Scientific GRAP Polyclonal Antibody
Rabbit polyclonal antibody targeting human GRAP protein. Validated for ICC/IF applications. Antigen affinity purified and supplied in PBS with glycerol. Suitable for research use to study cytoplasmic signaling pathways.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GRAP. Recombinant protein control fragment (Product #RP-105650) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663256 |
Product Specific Information
Immunogen sequence:
MESVALYSFQA TESDELAFNK GDTLKI
- Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 96%
Target Information
This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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