Thermo Fisher Scientific Aquaporin 5 Recombinant Rabbit Monoclonal Antibody (10V2Y1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

10V2Y1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 165-265 of human AQP5. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Aquaporin 5,uniProtId:P55064-1,ncbiNodeId:9606,antigenRange:165-265,antigenLength:265,antigenImageFileName:MA5-51429_Aquaporin_5_P55064-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51429_Aquaporin_5_P55064-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.01 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3094257

Product Specific Information

Immunogen Sequence: IGLSVTLGHL VGIYFTGCSM NPARSFGPAV VMNRFSPAHW VFWVGPIVGA VLAAILYFYL LFPNSLSLSE RVAIIKGTYE PDEDWEEQRE ERKKTMELTT R

Target Information

Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.