Thermo Fisher Scientific AMPK alpha 2 Polyclonal Antibody
Rabbit에서 생산된 AMPK alpha 2 폴리클로날 항체로, 인간 단백질에 반응. Western blot에 적합하며 에너지 대사 연구에 활용 가능. 고순도 항원 친화 크로마토그래피 정제 및 안정적 액상 형태로 제공.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AMPK alpha 2. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.06 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901984 |
Product Specific Information
- Centrifuge briefly prior to opening.
Target Information
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK).
AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits.
AMPK functions as an energy-sensing enzyme that monitors cellular energy status.
Under metabolic stress, AMPK is activated and phosphorylates acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), key enzymes regulating fatty acid and cholesterol biosynthesis.
Mouse studies indicate that this subunit may influence insulin sensitivity and maintain myocardial energy homeostasis during ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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