Thermo Fisher Scientific ARHGAP18 Polyclonal Antibody
ARHGAP18 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 인체 및 랫트 시료 반응성. 친화 크로마토그래피로 정제된 액상 항체로, -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ARHGAP18 (Accession Q8N392), corresponding to amino acid residues I516–D566. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851274 |
Product Specific Information
Antibody detects endogenous levels of total RHG18.
Target Information
ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins encoded in the human genome.
Rho proteins belong to the Ras superfamily, composed of over 50 members divided into six families: Ras, Sar, Rho, Ran, Rab, and Arf.
Rho GTPases regulate the actin cytoskeleton, influencing cell shape and migration.
ARHGAP18 is linked to Ras and EGFR-mediated proliferation, migration, and differentiation.
It is located on chromosome 6q22–24, a region associated with schizophrenia, suggesting a potential role in this condition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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