Thermo Fisher Scientific BCL11A Polyclonal Antibody
인간 BCL11A 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot 및 IHC에 적합. N-말단 합성 펩타이드로 면역원 제작. 고순도 Affinity Chromatography 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human BCL11A (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605488 |
Product Specific Information
- Peptide sequence: MSRRKQGKPQ HLSKREFSPE PLEAILTDDE PDHGPLGAPE GDHDLLTCGQ
- Sequence homology: Cow 100%, Dog 100%, Horse 100%, Human 100%, Mouse 100%, Pig 100%, Rat 100%, Zebrafish 100%
Target Information
This gene encodes a C2H2-type zinc-finger protein similar to mouse Bcl11a/Evi9. The mouse gene is a retroviral integration site in myeloid leukemia and may function as a leukemia disease gene through interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated and may be involved in lymphoma pathogenesis. Translocations associated with B-cell malignancies can deregulate its expression. Multiple transcript variants encoding several isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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