Thermo Fisher Scientific Aurora A/B/C Polyclonal Antibody
Aurora A/B/C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot에 적합하며 높은 특이성과 재현성을 제공합니다. 세포 분열 관련 키네이스 연구에 활용 가능하며, 액상 형태로 -20°C 보관이 권장됩니다.
- 카탈로그번호
- PA5120712
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500 – 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide of human AURKA/AURKB/AURKCAURKA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.23 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914284 |
Product Specific Information
Positive test controls include: HT-29, Rat testis.
Target Information
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a key regulator of mitosis.
The CPC complex ensures correct chromosome alignment and segregation, stabilizes microtubules, and regulates cytokinesis.
AURKB phosphorylates multiple CPC subunits and substrates (e.g., BIRC5, INCENP, CENPA, VIM, histone H3) to control mitotic processes.
Also involved in kinetochore localization of BUB1 and SGOL1 and regulation of p53 transcriptional activity.
Acts as a key regulator of active promoters in resting B- and T-lymphocytes.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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