Thermo Fisher Scientific PPP1R1B Monoclonal Antibody (3G11)
PPP1R1B(DARPP-32) 단백질을 인식하는 mouse monoclonal antibody(3G11). Western blot 및 ELISA에 사용 가능. Human 시료에 반응하며, affinity chromatography로 정제된 액상 형태. 보존제 미포함, -20°C 보관.
- 카탈로그번호
- H00084152-M03
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G11 |
| Immunogen | PPP1R1B (AAH01519, 1–168 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MLFRLSEHSS PEEEASPHQR ASGEGHHLKS KRPNPCAYTP PSLKAVQRIA ESHLQSISNL NENQASEEED ELGELRELGY PREEDEEEEE DDEEEEEEED SQAEVLKVIR QSAGQKTTCG QGLEGPWERP PPLDESERDG GSEDQVEDPA LSEPGEEPQR PSPSEPGT
Target Information
DARPP-32 is a dopamine (DA) and AMP-regulated ~32 kDa phosphoprotein associated with dopaminoceptive neurons. The protein inhibits Protein Phosphatase I when phosphorylated on Thr34, and acts as a PKA inhibitor when phosphorylated on Thr75. Phosphorylation of DARPP-32 plays a critical role in dopaminergic neurotransmission and is implicated in the actions of alcohol, caffeine, and Prozac®.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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