Thermo Fisher Scientific NFkB p52 Polyclonal Antibody
NFkB p52 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS(40% glycerol) 보존용액에 0.02% sodium azide 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NFKB2. Recombinant protein control fragment (Product # RP-102343) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790008 |
Product Specific Information
Immunogen sequence:
ICNYEGPAKI EVDLVTHSDP PRAHAHSLVG KQCSELGICA VSVGPKDMTA QFNNLGVLHV TKKNMMGTMI QKLQRQRLRS RPQGLTEAEQ RELEQEAKEL KKVMDLSIVR LRFSAFLRAS DGSFSLPLKP VISQP
Target Information
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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