
Thermo Fisher Scientific PKM2 Monoclonal Antibody (J.473.9)
PKM2 단백질을 인식하는 Rabbit 모노클로날 항체로 Western blot 및 면역세포화학(ICC/IF)에 적합. Human, Mouse, Rat 등 다양한 종에 반응. 합성 펩타이드 항원 기반으로 제작되었으며, 액상 형태로 -20°C 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
- Western Blot (WB): 1:1,000–1:5,000
- Immunocytochemistry (ICC/IF): 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | J.473.9 |
| Immunogen | Synthetic peptide corresponding to the sequence around Gly200 of human PKM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10982729 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
PKM2 (Pyruvate Kinase M2) catalyzes the conversion of phosphoenolpyruvate to pyruvate and ATP. It interacts with thyroid hormone, mediating metabolic effects, and binds Opa protein involved in bacterial adherence and invasion of human cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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