Thermo Fisher Scientific Phospho-Dopamine Receptor 2 (Ser317, Thr318) Polyclonal Antibody
인간 DRD2 수용체의 Ser317/Thr318 인산화 부위를 인식하는 폴리클로날 항체입니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human D2 around the phosphorylation site of Ser317/Thr318 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to suppression of reward behavior with morphine and reduction of spontaneous movements, resembling Parkinson’s disease.
Three alternatively spliced isoforms have been identified. DRD2 is expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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