
Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI1F8), TrueMAB
ABCB1 단백질을 인식하는 마우스 단일클론 항체로, Western blot에 적합합니다. Human 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/BSA/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications
- Western Blot (WB): 1:200 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 995–1280 of human ABCB1 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The membrane-associated protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intracellular membranes and are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is part of the MDR/TAP subfamily, involved in multidrug resistance. It functions as an ATP-dependent drug efflux pump with broad substrate specificity, responsible for decreased drug accumulation in multidrug-resistant cells and often mediating resistance to anticancer drugs. Additionally, it acts as a transporter in the blood-brain barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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