Thermo Fisher Scientific LC3B Polyclonal Antibody
LC3B 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(Frozen)에 사용 가능. 인간과 랫트 반응성. 동결건조 형태이며 보존제 없음. 자가포식 연구 및 신경발생, 대사, 암 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:1,000
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal residues of human MAP1LC3B conjugated to Blue Carrier Protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1076844 |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
After reconstitution, keep aliquots at -20°C for higher stability, and at 4°C with an appropriate antibacterial agent.
Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Target Information
LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3 B) in humans is encoded by the gene MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B).
LC3B is associated with microtubule assembly and plays an important role in neurogenesis and autophagy.
Autophagy is a process involving the degradation of cytoplasmic components through formation of autophagosomes that fuse with lysosomes.
LC3B may be involved in cancer, aging, metabolic and neurodegenerative disorders, as well as cardiovascular and pulmonary diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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