Thermo Fisher Scientific Calpain S1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 of human Calpain small subunit 1 (NP_0017401) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Calpain S1,uniProtId:P04632-1,ncbiNodeId:9606,antigenRange:69-268,antigenLength:268,antigenImageFileName:PA5-117054_Calpain_S1_P04632-1_Rabbit.svg,antigenImageFileNamePDP:PA5-117054_Calpain_S1_P04632-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.05 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901684

Product Specific Information

Positive Samples: BT-474, U-251MG, SKOV3, Mouse lung, Mouse heart, Mouse spleen, Rat lung

Immunogen sequence: ISEAAAQYNP EPPPPRTHYS NIEANESEEV RQFRRLFAQL AGDDMEVSAT ELMNILNKVV TRHPDLKTDG FGIDTCRSMV AVMDSDTTGK LGFEEFKYLW NNIKRWQAIY KQFDTDRSGT ICSSELPGAF EAAGFHLNEH LYNMIIRRYS DESGNMDFDN FISCLVRLDA MFRAFKSLDK DGTGQIQVNI QEWLQLTMYS

Target Information

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.