Thermo Fisher Scientific Calpain S1 Polyclonal Antibody
Calpain S1 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ELISA 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제 및 안정적 PBS/glycerol 저장 조건.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 69–268 of human Calpain small subunit 1 (NP_0017401) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901684 |
Product Specific Information
- Positive Samples: BT-474, U-251MG, SKOV3, Mouse lung, Mouse heart, Mouse spleen, Rat lung
- Immunogen sequence:
ISEAAAQYNP EPPPPRTHYS NIEANESEEV RQFRRLFAQL AGDDMEVSAT ELMNILNKVV TRHPDLKTDG FGIDTCRSMV AVMDSDTTGK LGFEEFKYLW NNIKRWQAIY KQFDTDRSGT ICSSELPGAF EAAGFHLNEH LYNMIIRRYS DESGNMDFDN FISCLVRLDA MFRAFKSLDK DGTGQIQVNI QEWLQLTMYS
Target Information
Calpains are a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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