Thermo Fisher Scientific KV4.3 (KCND3) Polyclonal Antibody
KCND3(KV4.3) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ELISA에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며 액상 형태로 제공됩니다. 고순도 Affinity Chromatography 정제, 안정적인 PBS/glycerol buffer 구성.
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Thermo Fisher Scientific KV4.3 (KCND3) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 521–655 of human KCND3 (NP_0049712) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8.17 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806706 |
Product Specific Information
- Immunogen sequence: MESSMQNYPS TRSPSLSSHP GLTTTCCSRR SKKTTHLPNS NLPATRLRSM QELSTIHIQG SEQPSLTTSR SSLNLKADDG LRPNCKTSQI TTAIISIPTP PALTPEGESR PPPASPGPNT NIPSIASNVV KVSAL
- Positive Samples: Mouse liver, Mouse brain, Rat liver
- Cellular Location: Cell membrane, Cell projection, Membrane, Multi-pass membrane protein, dendrite, sarcolemma
Target Information
Voltage-gated potassium (Kv) channels are a complex class of voltage-gated ion channels with diverse physiological roles including regulation of neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
Four sequence-related potassium channel genes—shaker, shaw, shab, and shal—have been identified in Drosophila, each with human homologs.
KCND3 encodes a member of the voltage-gated, shal-related subfamily forming A-type potassium ion channels, crucial for the repolarization phase of the action potential. Two isoforms are produced by alternative splicing.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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