Thermo Fisher Scientific ASB7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ASB7. Recombinant protein control fragment (Product #RP-102076). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ASB7,uniProtId:Q9H672-1,ncbiNodeId:9606,antigenRange:3-149,antigenLength:318,antigenImageFileName:PA5-51888_ASB7_Q9H672-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51888_ASB7_Q9H672-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638274

Product Specific Information

Immunogen sequence: HHHCRRNPEL QEELQIQAAV AAGDVHTVRK MLEQGYSPNG RDANGWTLLH FSAARGKERC VRVFLEHGAD PTVKDLIGGF TALHYAAMHG RARIARLMLE SEYRSDIINA KSNDGWTPLH VAAHYGRDSF VRLLLEFKAE VDPLSDK

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.