Thermo Fisher Scientific Human MMP-13 Recombinant Protein
Recombinant human MMP-13 protein expressed in E. coli. Useful as a control for anti-MMP-13 antibodies. Plays a key role in extracellular matrix degradation and bone development. Supplied in liquid form, stored at -80°C.
- 카탈로그번호
- RP77539
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human MMP-13 Recombinant Protein
Applications
- Assay-dependent
- Suitable for use as a control with anti-MMP-13 antibodies
Product Specifications
| 항목 | 내용 |
|---|---|
| Expression System | E. coli |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
RP-77539 is a purified recombinant human MMP-13 protein (catalytic domain), expressed in E. coli.
It may be used as a control with corresponding anti-MMP-13 antibodies.
Target Information
MMP13 (collagenase 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, tenascin-C (TNC), and aggrecan (ACAN).
MMP13 cleaves triple helical collagens (types I, II, and III) with the highest activity toward soluble type II collagen.
It can also degrade collagen types IV, XIV, and X.
MMP13 is involved in wound healing, tissue remodeling, cartilage degradation, bone development, mineralization, and ossification.
It is required for normal embryonic bone development and ossification.
Mutations in this gene may lead to disorders such as spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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