Thermo Fisher Scientific RDH5 Polyclonal Antibody
RDH5 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P)에서 검증됨. Human에 반응하며 Mouse, Bovine에 예측 반응. 항원 친화 크로마토그래피로 정제된 액상형 제품으로, 시각 색소 생합성 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 60–276 of Human RDH5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547624 |
Product Specific Information
- Recommended positive controls: A549, HeLa, Jurkat, NT2D1
- Predicted reactivity: Mouse (89%), Bovine (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases family.
This retinol dehydrogenase catalyzes the final step in the biosynthesis of 11-cis retinaldehyde, the universal chromophore of visual pigments.
Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness characterized by delayed regeneration of cone and rod photopigments.
Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 gene.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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