Thermo Fisher Scientific OLIG2 Polyclonal Antibody
OLIG2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트 반응성. WB, IHC 등 다양한 응용 가능. 정제된 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적.
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Thermo Fisher Scientific OLIG2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | Assay-dependent | View 6 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Flow Cytometry (Flow) | - | View 1 publication |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant mouse Olig2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | 0.2M Tris, pH 8, with 0.1M glycine |
| Contains | No preservative |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539836 |
Target Information
This gene encodes a basic helix-loop-helix transcription factor expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 suggested to play a role in learning deficits associated with Down syndrome.
Tissue Specificity:
Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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