
Thermo Fisher Scientific TEM8 Polyclonal Antibody
TEM8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트 반응성. WB와 IHC에 사용 가능. HepG2 lysate를 양성 대조로 권장. 냉장 또는 -20°C 장기 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (IHC) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to 13 amino acids near the center of human TEM8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11156593 |
Product Specific Information
- Recognizes all three isoforms of TEM8
- Suggested positive control: HepG2 cell lysate
- Compatible blocking peptide: PEP-0135 (for PA5-20016)
Target Information
TEM8 encodes a type I transmembrane protein and serves as a tumor-specific endothelial marker implicated in colorectal cancer.
It also functions as a receptor for Bacillus anthracis toxin (anthrax).
Binding of the protective antigen (PA) component to TEM8 mediates delivery of toxin components (EF and LF) into the cytosol, where they disrupt normal cellular processes.
Three alternatively spliced variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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