Thermo Fisher Scientific SLC24A2 Polyclonal Antibody
SLC24A2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 장기 보관 시 -20°C에서 안정적.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (Range: 374–470) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3092047 |
Product Specific Information
Immunogen sequence:
TEEGRFREKA SILHKIAKKK CHVDENERQN GAANHVEKIE LPNSTSTDVE MTPSSDASEP VQNGNLSHNI EGAEAQTADE EEDQPLSLAW PSETRKQ
Antigen sequence identity:
- Mouse: 89%
- Rat: 81%
Target Information
NCKX2, also known as solute carrier family 24 member 2 (SLC24A2), is part of a family of potassium-dependent sodium/calcium exchangers. These proteins contain two large hydrophilic loops and two sets of multiple transmembrane-spanning segments.
NCKX2 is expressed in neurons throughout the brain, with high expression in cone photoreceptors of the retina, hippocampal pyramidal cells, and deep nuclei of the cerebellum. It plays a critical role in light adaptation by transporting one calcium ion and one potassium ion in exchange for four sodium ions, controlling calcium concentration in the eye during light and darkness.
Additionally, NCKX2 regulates calcium levels in neuronal synapses and other areas with rapid calcium fluxes. Inactivation of NCKX2 may serve as a regulatory mechanism for sodium and calcium balance under varying physiological conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-145209_SLC24A2_Q9UI40-1_Rabbit.svg, PA5-145209_SLC24A2_Q9UI40-1_Rabbit_PDP.jpeg)
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