Thermo Fisher Scientific Synip Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Synip. Recombinant protein control fragment (Product #RP-93362). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Synip,uniProtId:Q6ZWJ1-1,ncbiNodeId:9606,antigenRange:465-552,antigenLength:553,antigenImageFileName:PA5-55020_Synip_Q6ZWJ1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55020_Synip_Q6ZWJ1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648142

Product Specific Information

Immunogen sequence: TPLGRNGRSI PATLALESKE LVKSVRALLD MDCLPYGWEE AYTADGIKYF INHVTQTTSW IHPVMSVLNL SRSEENEEDC SRELPNQK

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 81%.

Target Information

STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.