Thermo Fisher Scientific CALR Monoclonal Antibody (1G11-1A9)
CALR 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody(1G11-1A9). Western blot, IHC, ELISA 등에 적합하며 인간 시료 반응성. 고순도 Affinity Chromatography 정제, PBS buffer에 보존, 연구용 전용.
- 카탈로그번호
- H00000811-M01
- 판매단위
- pk
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Thermo Fisher Scientific CALR Monoclonal Antibody (1G11-1A9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G11-1A9 |
| Immunogen | CALR (AAH02500.1, 1–417 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MLLSVPLLLG LLGLAVAEPA VYFKEQFLDG DGWTSRWIES KHKSDFGKFV LSSGKFYGDE EKDKGLQTSQ DARFYALSAS FEPFSNKGQT LVVQFTVKHE QNIDCGGGYV KLFPNSLDQT DMHGDSEYNI MFGPDICGPG TKKVHVIFNY KGKNVLINKD IRCKDDEFTH LYTLIVRPDN TYEVKIDNSQ VESGSLEDDW DFLPPKKIKD PDASKPEDWD ERAKIDDPTD SKPEDWDKPE HIPDPDAKKP EDWDEEMDGE WEPPVIQNPE YKGEWKPRQI DNPDYKGTWI HPEIDNPEYS PDPSIYAYDN FGVLGLDLWQ VKSGTIFDNF LITNDEAYAE EFGNETWGVT KAAEKQMKDK QDEEQRLKEE EEDKKRKEEE EAEDKEDDED KDEDEEDEED KEEDEEEDVP GQAKDEL
Target Information
Calreticulin (CALR) is a calcium-binding chaperone that promotes folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. It transiently interacts with monoglucosylated glycoproteins synthesized in the ER and with the DNA-binding domain of NR3C1, mediating its nuclear export. CALR may also regulate maternal gene expression and oocyte maturation through calcium homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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