Thermo Fisher Scientific Alpha A Crystallin Polyclonal Antibody
Alpha A Crystallin 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 검증 완료. 인간 CRYAA 유래 합성 펩타이드로 면역화됨. Mouse 및 Rat 시료에서도 반응 예측. 1 mg/mL 농도의 액상 형태로 제공되며 -20°C 보관.
- 카탈로그번호
- PA568025
- 판매단위
- pk
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Thermo Fisher Scientific Alpha A Crystallin Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human CRYAA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691935 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found in vertebrate skeletal muscle tissue.
In the lens, their structural function is to assist in maintaining the proper refractive index.
The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma.
Alpha-crystallin is the largest and composed of two primary gene products—alpha-A and alpha-B.
Alpha-Crystallin comprises about 40% of total lens protein composition and functions as a chaperone to prevent aggregate formation that may lead to cataracts.
Phosphorylated states of alpha-crystallin may serve structural control and protein maintenance roles under cellular stress.
Alpha-B crystallin has been linked to Alexander’s disease, where it accumulates in brain cells of affected individuals.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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