Thermo Fisher Scientific SCCPDH Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SCCPDH. Recombinant protein control fragment (Product #RP-90307). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SCCPDH,uniProtId:Q8NBX0-1,ncbiNodeId:9606,antigenRange:105-230,antigenLength:429,antigenImageFileName:PA5-62239_SCCPDH_Q8NBX0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62239_SCCPDH_Q8NBX0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646990

Product Specific Information

Immunogen sequence: YGEPVIKACI ENGASCIDIS GEPQFLELMQ LKYHEKAADK GVYIIGSSGF DSIPADLGVI YTRNKMNGTL TAVESFLTIH SGPEGLSIHD GTWKSAIYGF GDQSNLRKLR NVSNLKPVPL IGPKLK

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 87%.

Target Information

SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family. The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C. elegans, and maps to human chromosome 1q44. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Stickler syndrome, Parkinson`s, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.