Thermo Fisher Scientific Villin (GI-Mucosal and Urogenital Brush Border Marker) Monoclonal Antibody (VIL1/1325)
Villin 단백질을 인식하는 단클론 항체로, 위장관 및 비뇨생식계 브러시보더 표지자로 사용됩니다. Western blot 및 IHC 분석에 적합하며, 고순도의 Protein A/G 정제 항체입니다. 인간 시료 반응성이 있으며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.25–0.5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VIL1/1325 |
| Immunogen | Recombinant human Villin fragment (around aa179–311) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Villin is part of the cytoskeleton associated with the microvillar actin core bundle of the gastrointestinal and renal brush border. It interacts with actin in a Ca²⁺ and phosphoinositide-regulated manner. Villin serves as a specific marker for adenocarcinomas of the gastrointestinal tract and pancreas and is also expressed in certain Merkel cell tumors and adenocarcinomas of the lung, prostate, ovary, and kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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