Thermo Fisher Scientific HSD17B4 Monoclonal Antibody (8E5AB11)
HSD17B4 단백질을 인식하는 Thermo Fisher Scientific의 mouse monoclonal antibody (clone 8E5AB11). ICC/IF, ELISA, IP 등 다양한 응용 가능. Human MFE2를 면역원으로 사용하며, 비결합형 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific HSD17B4 Monoclonal Antibody (8E5AB11)
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 4 µg/mL | |
| ELISA | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8E5AB11 |
| Immunogen | Human MFE2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| RRID | AB_2535887 |
Target Information
Peroxisomal multifunctional enzyme type 2 is a protein encoded by the HSD17B4 gene in humans.
This bifunctional enzyme is involved in the peroxisomal beta-oxidation pathway for fatty acids and catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids.
Defects in this gene that affect peroxisomal fatty acid beta-oxidation activity cause D-bifunctional protein deficiency (DBPD).
A pseudogene of this gene exists on chromosome 8, and multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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