Thermo Fisher Scientific SEC62 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 258-399 of human SEC62 (NP_0032531) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SEC62,uniProtId:Q99442-1,ncbiNodeId:9606,antigenRange:258-399,antigenLength:399,antigenImageFileName:PA5-116868_SEC62_Q99442-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116868_SEC62_Q99442-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.66 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901499

Product Specific Information

Positive Samples: HeLa, MCF7

Immunogen sequence: GRHHFWFLPN LTADVGFIDS FRPLYTHEYK GPKADLKKDE KSETKKQQKS DSEEKSDSEK KEDEEGKVGP GNHGTEGSGG ERHSDTDSDR REDDRSQHSS GNGNDFEMIT KEELEQQTDG DCEEDEEEEN DGETPKSSHE KS

Target Information

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.