Thermo Fisher Scientific Claudin 19 Polyclonal Antibody
Claudin 19 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응합니다. Western blot에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS 기반 액상 형태로 제공되며, 안정적인 장기 보관이 가능합니다.
- 카탈로그번호
- PA540751
- 판매단위
- pk
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Thermo Fisher Scientific Claudin 19 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.2–1 µg/mL
Publications: - References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human CLDN19 (aa 175–224) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606667 |
Product Specific Information
Peptide sequence:
AVLGGSFLCC TCPEPERPNS SPQPYRPGPS AAAREPVVKL PASAKGPLGV
Sequence homology:
Cow: 86% | Dog: 100% | Guinea Pig: 86% | Horse: 93% | Human: 100% | Mouse: 79% | Pig: 100% | Rabbit: 100% | Rat: 93%
Target Information
The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO), a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria, and nephrocalcinosis, associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia, and nystagmus.
Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
[provided by RefSeq, Jun 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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