Thermo Fisher Scientific NALP14 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NALP14. Recombinant protein control fragment (Product #RP-97404). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NALP14,uniProtId:Q86W24-1,ncbiNodeId:9606,antigenRange:69-171,antigenLength:1093,antigenImageFileName:PA5-58802_NALP14_Q86W24-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58802_NALP14_Q86W24-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644453

Product Specific Information

Immunogen sequence: EKAWSVSLKI FGKMNLKDLC ERAKEEINWS AQTIGPDDAK AGETQEDQEA VLGDGTEYRN RIKEKFCITW DKKSLAGKPE DFHHGIAEKD RKLLEHLFDV DVK

Highest antigen sequence identity to the following orthologs: Mouse - 24%, Rat - 26%.

Target Information

NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.