Thermo Fisher Scientific MPRIP/M-RIP Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–10 µg/mg lysate

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from the date of receipt.

Target Information

MPRIP targets myosin phosphatase to the actin cytoskeleton and is required for regulation of the actin cytoskeleton by RhoA and ROCK1.
Depletion leads to increased stress fibers in smooth muscle cells due to stabilization of actin fibers by phosphorylated myosin.
Overexpression of MRIP or its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.