Thermo Fisher Scientific MPRIP/M-RIP Polyclonal Antibody
Rabbit Polyclonal 항체로, MPRIP 단백질을 인식하여 Western blot 및 Immunoprecipitation에 적합합니다. 액상 형태이며 1 mg/mL 농도로 제공됩니다. 4°C에서 보관하며, 세포골격 조절 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 550 to 600 of human Myosin phosphatase Rho-interacting protein (MPRIP) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
MPRIP targets myosin phosphatase to the actin cytoskeleton and is required for regulation of the actin cytoskeleton by RhoA and ROCK1.
Depletion leads to increased stress fibers in smooth muscle cells due to stabilization of actin fibers by phosphorylated myosin.
Overexpression of MRIP or its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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