Thermo Fisher Scientific HCG-beta Recombinant Rabbit Monoclonal Antibody (HCGb, 1996R)
Recombinant rabbit monoclonal antibody targeting hCG beta for immunohistochemistry applications. High specificity to human hCGβ, purified via Protein A/G. Supplied as liquid form, 200 µg/mL concentration, optimized for formalin-fixed tissue staining.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HCGb, 1996R |
| Immunogen | Recombinant full-length hCG beta protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature (RT).
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at RT for 20 minutes.
Target Information
hCG beta is the beta chain of human chorionic gonadotropin (hCG), a 40 kDa glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10–12 days after conception.
hCG consists of non-covalently associated alpha and beta subunits. The alpha subunit is similar to those of pituitary hormones (FSH, LH, TSH), while the beta subunit confers biological specificity.
During early pregnancy, hCG stimulates the corpus luteum to produce progesterone, maintaining the secretory endometrium.
hCG is detectable only in trace amounts in non-pregnant urine and serum but rises sharply during pregnancy.
Diseases associated with hCG dysfunction include gestational trophoblastic tumor and hydatidiform mole.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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