Thermo Fisher Scientific PTPRU Polyclonal Antibody
Human PTPRU 단백질을 인식하는 Rabbit Polyclonal Antibody로 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, 0.1 mg/mL 농도의 액상 형태. PBS(40% glycerol) 버퍼에 보관하며, 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PTPRU. Recombinant protein control fragment (Product #RP-94968). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646138 |
Product Specific Information
Immunogen sequence:
TFEEASDPAV PCEYSQAQYD DFQWEQVRIH PGTRAPADLP HGSYLMVNTS QHAPGQRAHV IFQSLSENDT HCVQFSYFLY SRDG
- Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 90%
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This receptor-type PTP contains an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains.
The extracellular region includes a MAM domain, Ig-like, and fibronectin type III-like repeats.
It is implicated in cell-cell recognition and adhesion, with studies in mice suggesting a role in early neural development.
Expression is regulated by PMA or calcium ionophore in Jurkat T lymphoma cells.
Alternatively spliced transcript variants have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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