Thermo Fisher Scientific Septin 9 Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: 1:50–1:500

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Monkey, Crab-eating macaque, and White-tufted-ear marmoset

Target Information

The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses: large Mafs (vMaf, cMaf, MafB, and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucine zipper motifs, allowing homo- and heterodimerization with other bZip transcription factors. Large Mafs possess an acidic transactivation domain absent in small Maf proteins.
Small Maf proteins can act as positive regulators of transcription by targeting active dimerization partners to DNA regulatory elements, or as negative regulators by forming homodimers or recruiting repressors.
Human MafF was isolated from a human myometrium cDNA library and encodes a 164-amino-acid protein with an extended leucine zipper structure. The small Maf proteins are involved in development, differentiation, hematopoiesis, and stress response, regulating stress via different mechanisms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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