Thermo Fisher Scientific Phospho-NBS1 (Ser278) Polyclonal Antibody
Thermo Fisher Scientific의 Phospho-NBS1 (Ser278) Polyclonal Antibody는 인간 Nibrin의 Ser278 인산화 부위를 인식하는 항체입니다. Western blot, ICC/IF, peptide-ELISA에 사용 가능하며, 고순도 Rabbit IgG 폴리클로날 항체로 연구용에 적합합니다.
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Thermo Fisher Scientific Phospho-NBS1 (Ser278) Polyclonal Antibody
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| peptide-ELISA (pep-ELISA) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human Nibrin around the phosphorylation site of Ser278 (T-N-SP-Q-T) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555484 |
Target Information
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity. It reveals a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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